Longitudinal study of the Campinas and Ermelino Matarazzo cohorts of the FIBRA study: predictors and outcomes of frailty among the elderly in Brazil

• Grant number: 17/23245-0
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• Start date: April 01, 2018
• End date: June 14, 2020
• Field of knowledge: Interdisciplinary Subjects
• Principal Investigator: Monica Sanches Yassuda
• Grantee: Flávia Silva Arbex Borim
• Host Institution: Faculdade de Ciências Médicas (FCM). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
• Associated research grant: 16/00084-8 - Longitudinal study of the Campinas and Ermelino Matarazzo cohorts of the FIBRA study: predictors and outcomes of frailty among the elderly in Brazil, AP.TEM

Abstract

Context: Frailty is a clinical syndrome associated with negative health outcomes. The study of frailty among Brazilian elderly is of particular relevance, as they live in different conditions compared to European and North American elderly, in terms of income, education, access to health and social opportunities. These differences can change the profile of this syndrome in Brazil, as well as its antecedents and outcomes. Objectives: This investigation aims to carry out the follow-up assessment after seven years of two cohorts of seniors who were enrolled in the population-based study FIBRA coordinated by UNICAMP with data collection conducted between 2008 and 2009 in Campinas (n = 900) and Ermelino Matarazzo ( n = 384). The following research questions should be answered: 1. Among the robust seniors in 2008/2009, how many have become pre-frail and frail and which factors, among a set of sociodemographic, psychological, social and health parameters, predict frailty?; 2. The pre-frailty and frailty identified in 2008/2009, in a portion of the original sample, are associated with which health outcomes after seven years (e.g., death, immobility, functional dependency, dementia, hospitalization)? 3. Among the robust, pre-frail and frail participants in 2008/2009, how many have developed major or mild neurocognitive disorder and which factors, among a set of sociodemographic, psychological, social and health parameters predict these conditions? Methods: The participants of the original sample will be contacted by letter and then by telephone to identify the participant's current status and to schedule a home interview. The original protocol of the FIBRA study, after minor adjustments, will be applied to collect information about demographics, health, neurocognitive and psychiatric profile, anthropometry, frailty makers, psychosocial characteristics and nutritional intake. The family of the participant will be interviewed to obtain information regarding the neurocognitive profile and should be the main informant if the participant is unable to participate. This longitudinal study will generate information on factors that predict long-term frailty among the robust elderly in the baseline and the outcomes of frailty among the elderly initially identified as frail or pre-frail. This investigation should provide information about factors that might help to delay or mitigate the negative health outcomes associated with frailty.

Scientific publications

(5)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

DE ASSUMPCAO, DANIELA; FERRAZ, ROSEMEIRE DE OLANDA; ARBEX BORIM, FLAVIA SILVA; NERI, ANITA LIBERALESSO; STOLSES BERGAMO FRANCISCO, PRISCILA MARIA. Waist circumference, waist-to-height ratio and overweight cut-off points: a cross-sectional study with elderly people in seven Brazilian cities, 2008-2009. EPIDEMIOLOGIA E SERVICOS DE SAUDE, v. 29, n. 4, 2020. (17/23245-0)

PIVETTA, N. R. S.; MARINCOLO, J. C. S.; NERI, A. L.; APRAHAMIAN, I; YASSUDA, M. S.; BORIM, F. S. A.. Multimorbidity, frailty and functional disability in octogenarians: A structural equation analysis of relationship. ARCHIVES OF GERONTOLOGY AND GERIATRICS, v. 86, JAN-FEB 2020. (17/23245-0)

BUARQUEI, GISELLE LAYSE ANDRADE; BORIM, FLAVIA SILVA ARBEX; NERI, ANITA LIBERALESSO; YASSUDA, MONICA SANCHES; DE MELO, RUTH CALDEIRA. Relationships between self-reported dyspnea, health conditions and frailty among Brazilian community-dwelling older adults: a cross-sectional study. São Paulo Medical Journal, v. 140, n. 3, p. 10-pg., 2022-05-01. (17/23245-0)

DANIELA DE ASSUMPÇÃO; ROSEMEIRE DE OLANDA FERRAZ; FLÁVIA SILVA ARBEX BORIM; ANITA LIBERALESSO NERI; PRISCILA MARIA STOLSES BERGAMO FRANCISCO. Pontos de corte da circunferência da cintura e da razão cintura/estatura para excesso de peso: estudo transversal com idosos de sete cidades brasileiras, 2008-2009. Epidemiol. Serv. Saúde, v. 29, n. 4, 2020-07-17. (17/23245-0)

ARBEX BORIM, FLAVIA SILVA; DE ASSUMPCAO, DANIELA; NERI, ANITA LIBERALESSO; TAVARES BATISTONI, SAMILA SATHLER; STOLSES BERGAMO FRANCISCO, PRISCILA MARIA; YASSUDA, MONICA SANCHES. Impact of functional capacity on change in self-rated health among older adults in a nine-year longitudinal study. BMC GERIATRICS, v. 21, n. 1, NOV 4 2021. (16/00084-8, 17/23245-0)