Priapism and voiding dysfunction in sickle cell disease: pathophysiology and new drug candidates

• Grant number: 18/06243-6
• Support Opportunities: Scholarships in Brazil - Young Researchers
• Start date: April 01, 2018
• End date: July 31, 2019
• Field of knowledge: Biological Sciences - Pharmacology - Autonomic Pharmacology
• Principal Investigator: Fábio Henrique da Silva
• Grantee: Fábio Henrique da Silva
• Host Institution: Centro de Hematologia e Hemoterapia (HEMOCENTRO). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
• Associated research grant: 17/08122-9 - Priapism and voiding dysfunction in Sickle Cell Disease: pathophysiology and new drug candidates, AP.JP

Scientific publications

(4)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

MUSICKI, BILJANA; ANELE, UZOMA A.; CAMPBELL, JEFFREY D.; KARAKUS, SERKAN; SHIVA, SRUTI; SILVA, FABIO H.; BURNETT, ARTHUR L.. Dysregulated NO/PDE5 signaling in the sickle cell mouse lower urinary tract: Reversal by oral nitrate therapy. Life Sciences, v. 238, DEC 1 2019. (17/08122-9, 18/06243-6)

SILVA, FABIO HENRIQUE; FERTRIN, KLEBER YOTSUMOTO; ALEXANDRE, EDUARDO COSTA; CALMASINI, FABIANO BERALDI; FRANCO-PENTEADO, CARLA FERNANDA; COSTA, FERNANDO FERREIRA. Impairment of Nitric Oxide Pathway by Intravascular Hemolysis Plays a Major Role in Mice Esophageal Hypercontractility: Reversion by Soluble Guanylyl Cyclase Stimulator. Journal of Pharmacology and Experimental Therapeutics, v. 367, n. 2, p. 194-202, NOV 1 2018. (14/00984-3, 18/06243-6, 17/08122-9)

KARAKUS, SERKAN; ANELE, UZOMA A.; SILVA, FABIO H.; MUSICKI, BILJANA; BURNETT, ARTHUR L.. Urinary dysfunction in transgenic sickle cell mice: model of idiopathic overactive bladder syndrome. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, v. 317, n. 3, p. E540-E546, SEP 2019. (18/06243-6, 17/08122-9)

SILVA, FABIO H.; GODOY, BEATRIZ P. B.; ALEXANDRE, EDUARDO C.; CALMASINI, FABIANO B.; DOS SANTOS, JEAN L.; COSTA, FERNANDO F.. Effect of treatment with a new nitric oxide donor, a hybrid derived from resveratrol and furoxan (E)-4-(4-(4-methoxystyryl)phenoxy)-3-methyl-1,2,5-oxadiazole-2-oxide, on priapism in sickle cell mouse and nitric oxide-deficient mouse. JOURNAL OF TRANSLATIONAL MEDICINE, v. 17, n. 1, p. 1-pg., 2019-08-15. (17/08122-9, 18/06243-6)