Hospital automation applied to the development of microelectrode arrays for analysis of the bioelectric activity of cardiac cell in cultivation

• Grant number: 18/02134-8
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: April 01, 2018
• End date: March 31, 2019
• Field of knowledge: Engineering - Electrical Engineering - Electrical, Magnetic and Electronic Measurements, Instrumentation
• Principal Investigator: Fernando Luis de Almeida
• Grantee: Yann Lima de Moraes
• Host Institution: Faculdade de Tecnologia de Itaquera Miguel Reale (FATEC Itaquera). Centro Paula Souza (CEETEPS). Secretaria de Desenvolvimento Econômico (São Paulo - Estado). São Paulo , SP, Brazil

Abstract

In this scientific research, it will be presented a project to manufacture of an array composed by 60 gold microelectrodes (measuring microsensors with 50 µm each, and the total measuring region is 5 mm in radius) and by a reference electrode (1 mm2 in area), that were defined on a printed-circuit board (PCB) with 28.4 wide and 28.4 length. This array will be used to verication and recording of cardiac action potentials in an aqueous and electrolytic solution, similar of a cardiac cell in cultivation. Also, a shielded device to electromagnetic noises will be improved to connect the array, allowing the capture of electrical signals by the microelectrodes. Finally, biocompatibility tests with the structures of arrays will be performanced. (AU)