Perinatal depression and maternal and infant mortality

• Grant number: 18/07578-1
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• Start date: June 01, 2018
• End date: May 31, 2020
• Field of knowledge: Health Sciences - Medicine - Psychiatry
• Agreement: Fundação Seade
• Principal Investigator: Cristina Marta Del-Ben
• Grantee: Marcos Gonçalves de Rezende
• Host Institution: Faculdade de Medicina de Ribeirão Preto (FMRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
• Associated research grant: 17/03771-9 - Mortality in mental disorders, AP.TEM

Abstract

Depressive episodes during gestation and the postpartum period are highly prevalent, especially in low- and middle-income countries, with serious consequences for the mother-baby binomial (Gelaye et al., Lancet Psychiatry, 2016; 3 (10): 973- 982). Suicide rates during the postnatal period are similar to those observed in other phases of the female life cycle, which speak against the common sense that gestation and motherhood would be protective events for the occurrence of mental disorders (Surkan et al. Best Pract Res Clin Obstet Gynaecol, 2016; 36: 156-168). In addition, although there are few studies, there is evidence to suggest an association between maternal depression and infant mortality (Surkan et al., Best Practice Res Clin Obstet Gynaecol, 2016, 36: 156-168). Estimates of the association between maternal depression and maternal and infant mortality are particularly important in low- and middle-income countries where other risk factors due to unfavorable socioeconomic conditions are more prevalent. This information can contribute significantly to the adequate planning of public policies aimed at the protection of the mental health of mother and child.Thus, Perinatal depression and maternal and infant mortality, aimed at: (a) investigating the association of maternal depression, identified during pregnancy and/or in the postpartum, with information on the deaths of mothers and children, thus constituting two cohorts, and (b) identification, a five-year period, of biological, clinical, and social factors associated with mortality of depressed mothers during gestation and/or the postpartum period and their respective children, compared with euthymic women during gestation and postpartum. (AU)

Scientific publications

(4)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

MARANHO, MARIA CLARA DE MORAIS FALEIROS; GUAPO, VINICIUS GUANDALINI; DE REZENDE, MARCOS GONSALVES; VIEIRA, CAROLINA SALES; BRANDAO, MARCUS LIRA; GRAEFF, FREDERICO GUILHERME; LOVICK, THELMA; DEL-BEN, CRISTINA MARTA. Low doses of fluoxetine for the treatment of emotional premenstrual syndrome: a randomized double-blind, placebo-controlled, pilot study. PSYCHONEUROENDOCRINOLOGY, v. 157, p. 8-pg., 2023-11-01. (18/07578-1, 14/50829-4)

DA ROZA, DAIANE LEITE; DE REZENDE, MARCOS GONCALVES; MAIA BARROS, REGIS ERIC; DE AZEVEDO-MARQUES, JOAO MAZZONCINI; FERREIRA SANTOS, JAIR LICIO; CORREIA MORAIS, LILIAN CRISTINA; DE CARVALHO FERREIRA, CARLOS EUGENIO; WALDVOGEL, BERNADETTE CUNHA; MENEZES, PAULO ROSSI; DEL-BEN, CRISTINA MARTA. Excess mortality in a cohort of Brazilian patients with a median follow-up of 11 years after the first psychiatric hospital admission. Social Psychiatry and Psychiatric Epidemiology, v. 58, n. 2, p. 12-pg., 2022-05-31. (18/07578-1, 18/07581-2, 17/03771-9)

FIGUEIREDO DE PAULA EDUARDO, JULIANA ARANTES; FIGUEIREDO, FELIPE PINHEIRO; DE REZENDE, MARCOS GONCALVES; DA ROZA, DAIANE LEITE; DE FREITAS, STELLA FELIPPE; LUCENA BATISTA, ROSANGELA FERNANDES; MOURA DA SILVA, ANTONIO AUGUSTO; BARBIERI, MARCO ANTONIO; CAVALLI, RICARDO CARVALHO; BETTIOL, HELOISA; et al. Preterm birth and postpartum depression within 6 months after childbirth in a Brazilian cohort. ARCHIVES OF WOMENS MENTAL HEALTH, v. 25, n. 5, p. 13-pg., 2022-07-18. (18/07578-1, 18/07581-2, 08/53593-0)

FIGUEIREDO DE PAULA EDUARDO, JULIANA ARANTES; DE REZENDE, MARCOS GONCALVES; MENEZES, PAULO ROSSI; DEL-BEN, CRISTINA MARTA. Preterm birth as a risk factor for postpartum depression: A systematic review and meta-analysis. Journal of Affective Disorders, v. 259, p. 392-403, DEC 1 2019. (18/07578-1)