Mapping the cortical representation of posture in stroke patients

• Grant number: 18/08609-8
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• Start date: June 01, 2018
• End date: February 28, 2019
• Field of knowledge: Engineering - Biomedical Engineering - Bioengineering
• Principal Investigator: Antonio Carlos Roque da Silva Filho
• Grantee: Rodrigo Pereira Rocha
• Host Institution: Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto (FFCLRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
• Associated research grant: 13/07699-0 - Research, Innovation and Dissemination Center for Neuromathematics - NeuroMat, AP.CEPID

Abstract

Postural control has classically been thought as achieved solely by mechanisms of feedback. However, since sensory feedback loops are slow and relatively noisy (Wolpert and Miall, 1996; Kawato et al., 1987), fast and coordinated body movements cannot be executed solely under feedback control. A modern view of motor control (called the internal model theory) proposes that the brain needs to acquirean inverse dynamics model of body movements to be controlled through motor learning, after which motor control can be executed in a pure feedforward (or predictive) manner (Kawato et al., 1987). This fundamental feature would allow modeling the capacity for plastic change and adaptation found in motor systems (Shadmehr and Krakauer, 2008), maintained throughout life by learning and learning-to-predictmechanisms.

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

ROCHA, RODRIGO P.; KOCILLARI, LOREN; SUWEIS, SAMIR; DE GRAZIA, MICHELE DE FILIPPO; DE SCHOTTEN, MICHEL THIEBAUT; ZORZI, MARCO; CORBETTA, MAURIZIO. Recovery of neural dynamics criticality in personalized whole-brain models of stroke. NATURE COMMUNICATIONS, v. 13, n. 1, p. 18-pg., 2022-06-27. (18/08609-8)

ROCHA, RODRIGO P.; KOCILLARI, LOREN; SUWEIS, SAMIR; CORBETTA, MAURIZIO; MARITAN, AMOS. Homeostatic plasticity and emergence of functional networks in a whole-brain model at criticality. SCIENTIFIC REPORTS, v. 8, OCT 24 2018. (18/08609-8)