| Grant number: | 18/25925-0 |
| Support Opportunities: | Scholarships in Brazil - Scientific Initiation |
| Start date: | March 01, 2019 |
| End date: | January 31, 2020 |
| Field of knowledge: | Engineering - Chemical Engineering - Chemical Process Industries |
| Principal Investigator: | Adriano Pinto Mariano |
| Grantee: | Gabriela Matias |
| Host Institution: | Faculdade de Engenharia Química (FEQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil |
| Associated research grant: | 15/20630-4 - Biorefinery development integrated to a bioethanol sugar cane plant with zero CO2 emission: routes to convert renewable resources to bio-products and bio-electricity, AP.TEM |
Abstract The butanol production by fermentation is limited to the low economic competitivenessassociated with high prices of raw materials, energy inefficiency, low yield and productivity. The use of sugarcane bagasse hemicellulosichydrolysate (C5 sugars, mainly xylose) and molasses as raw materials, they are low cost options and there is not competition for raw materials ofsecond generation ethanol production, because the C5 sugars are not fermentable by the microorganismSaccharomyces cerevisiae. One option that is being studied for this problem, it is the conversion of hemicellulosichydrolysate to butanol by ABE fermentation (acetone/butanol/ethanol).However, this alternative also has its own challenges. The hemicellulosichydrolysate is diluted (~20 gL-1 xylose) and contains microbial inhibitors generated on pretreatment, thus preventing the efficient conversion of xylose. The bacteria of the genusClostridium have the ability to naturally metabolize the present pentoses and make ABE fermentation more viable in terms of productivity. Therefore, the main objective of this scientific initiation project is to increase the conversion efficiency of the sugarcane bagasse hemicellulosichydrolysate(non-detoxified) into n-butanol. To achieve this purpose, it will be developed a fermentation strategy that combining three elements: mixing of hemicellulosichydrolysate with molasses, passive cell immobilization using the sugarcane bagasse as cell carrier and fed-batch operation. Thus, the low yield andproductivity can be solved by evaluating the conversion of the hemicellulosichydrolysatetobutanol and applying cell immobilization techniques that promote high cell concentration. | |
| News published in Agência FAPESP Newsletter about the scholarship: | |
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