Development of a novel high entropy alloy based on TiZrNbTaMn for potential biomedical application

• Grant number: 18/24931-7
• Support Opportunities: Scholarships in Brazil - Master
• Start date: May 01, 2019
• End date: July 31, 2021
• Field of knowledge: Engineering - Materials and Metallurgical Engineering - Physical Metallurgy
• Principal Investigator: Diego Rafael Nespeque Correa
• Grantee: Jhuliene Elen Muro Torrento
• Host Institution: Faculdade de Ciências (FC). Universidade Estadual Paulista (UNESP). Campus de Bauru. Bauru , SP, Brazil

Abstract

Biomedical titanium (Ti) alloys have been developed mainly for orthopedic and dental implants, combining better mechanical and electrochemical properties, and biocompatibility than others commercial biomaterials, such as stainless steel 316L and Co-Cr-Mo alloys. However, the actual Ti alloys do not avoid common problems happened in implantable materials, such as stress shielding effect, low tribocorrosion resistance and toxicity by release of metallic ion debris at long-term. In the last years, high entropy alloys (HEAs), composed by at least five elements in proportion near equimolar, have been employed for aviation and structural industries. HEAs have been recognized by their high strength, ductility and corrosion resistance, which has attracted attention by the biomedical industry. However, the properties of developed HEAs do not match with the requirements for use as biomaterial. Furthermore, there are not a deep understanding about the mechanisms of crystallization and solidification of the bulk, and the interactions between their surfaces with human bone cells and tissues. This project aims to characterize the crystalline structure, microstructure and mechanical properties of a novel biomedical high entropy alloy, composed by non-toxic elements (Ti, Nb, Zr, Ta and Mn), in equiatomic proportion, for possible application as biomedical implants. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

TORRENTO, JHULIENE ELEN; DE SOUSA, TIAGO DOS SANTOS PEREIRA; CRISTINO DA CRUZ, NILSON; SANTOS DE ALMEIDA, GERSON; ZAMBUZZI, WILLIAN FERNANDO; GRANDINI, CARLOS ROBERTO; NESPEQUE CORREA, DIEGO RAFAEL. Development of non-equiatomic Bio-HEAs based on TiZrNbTa-(Mo and Mn). APL Materials, v. 10, n. 8, p. 10-pg., 2022-08-01. (18/24931-7)