Distortion product otoacoustic emission measurements: reflection and distortion component analysis in children exposed to secondhand smoke

• Grant number: 19/27362-6
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: August 01, 2020
• End date: October 31, 2021
• Field of knowledge: Health Sciences - Speech Therapy
• Principal Investigator: Alessandra Spada Durante
• Grantee: Camila Aparecida Dantas Lima
• Host Institution: Faculdade de Ciências Médicas da Santa Casa de São Paulo (FCMSCSP). Fundação Arnaldo Vieira de Carvalho. São Paulo , SP, Brazil

Abstract

The rate of students exposed to secondhand smoke in the home environment in Brazil still high: 26.2%. Passive smoking has been characterized as a risk factor for hearing loss. Carbon monoxide contained in cigarette smoke produces an ototoxic effect that affects the functioning of the auditory system, specifically the functioning of the outer hair cells. When healthy, the outer hair cells electromotility along with non-linear cochlear physiology generate otoacoustic emissions (OAE) as a response, which have distinct generation mechanisms: reflection and distortion component. Rao by distortion product otoacoustic emissions (DPOAE) investigated the effect of ototoxic salicylate on the cochlear system and reported that the reflection component would be more vulnerable. In 2019 Durante studied the effect of secondhand smoke on newborns through DPOAE and TEOAE and the impact of smoking could only be observed by reducing TEOAE responses, while DPOAE did not obtain statistically significant results between groups, however only the overall DPOAE response was analyzed. This research intends to analyze the behavior of the reflection and distortion components of the DPOAE of a group of children, which are exposed and not exposed to secondhand smoke and hypothesizes that there is an inequality between the impact on the components, and the reflection component may be more vulnerable. than the distortion component when exposed to cigarette smoke ototoxic agents. (AU)