Determinants associated with multidrug-resistant tuberculosis in the Paraná State prison system

• Grant number: 20/03361-8
• Support Opportunities: Scholarships in Brazil - Master
• Start date: July 01, 2020
• End date: September 30, 2020
• Field of knowledge: Health Sciences - Collective Health - Epidemiology
• Principal Investigator: Ricardo Alexandre Arcêncio
• Grantee: Márcio Souza dos Santos
• Host Institution: Escola de Enfermagem de Ribeirão Preto (EERP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil

Abstract

Tuberculosis (TB) remains a public health problem in the world, due to its magnitude, transcendence and vulnerability. In Brazil, in 2017, 69,569 new cases of TB with an incidence coefficient of 33.5 cases/100 thousand inhabitants, between the period 2008 to 2017. This is a retrospective cohort study, the study population will consist of all cases of MDR-TB of individuals by filling in the "Type of address" field of your notification form, with the information "Inmate" or those that are characterized as institutionalized in the Paraná state prison system. The data will be collected through the TB case notification forms from 2008 to 2019 from the Tuberculosis Patient Control System and the Notifiable Diseases Information System, allocated in the Epidemiological Surveillance Department of the Paraná State Health Secretariat and PNCTof the Ministry of Health allocated in Brasília (DF). An exploratory approach to the data will be performed with the removal of duplicates in TB case reports. Through the individual information contained in the PPL notification form, a descriptive analysis will be performed with calculation of absolute and relative frequencies of TB-MDR cases. The treatment outcomes of MDR-TB patients in prison units will be described. Then, the incidence rate of MDR-TB cases will be calculated within the prison units in the state of Paraná. To identify the factors associated with the emergence of TB-MDR in the PPL, a binary logistic regression will be conducted. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

DOS SANTOS, MARCIO SOUZA; PIERI, FLAVIA MENEGUETTI; BERRA, THAIS ZAMBONI; SCHOLZE, ALESSANDRO ROLIM; VIEIRA RAMOS, ANTONIO CARLOS; CRISPIM, JULIANE DE ALMEIDA; GIACOMET, CLOVIS LUCIANO; ALVES, YAN MATHIAS; PAULINO DA COSTA, FERNANDA BRUZADELLI; DIAS MOURA, HERIEDERSON SAVIO; et al. Acquired and Transmitted Multidrug-Resistant Tuberculosis among the Incarcerated Population and Its Determinants in the State of Parana-Brazil. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, v. 19, n. 22, p. 12-pg., 2022-11-01. (20/03361-8)

DOS SANTOS, MARCIO SOUZA; BERRA, THAIS ZAMBONI; SCHOLZE, ALESSANDRO ROLIM; DELPINO, FELIPE MENDES; VIEIRA RAMOS, ANTONIO CARLOS; ALVES, YAN MATHIAS; PAULINO DA COSTA, FERNANDA BRUZADELLI; CRISPIM, JULIANE DE ALMEIDA; GIACOMET, CLOVIS LUCIANO; DIAS MOURA, HERIEDERSON SAVIO; et al. Trend and Spatial Distribution of Drug-Resistant Tuberculosis in Liberty-Deprived Populations in the State of Parana, Brazil. TROPICAL MEDICINE AND INFECTIOUS DISEASE, v. 7, n. 10, p. 10-pg., 2022-10-01. (20/03361-8)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

SANTOS, Márcio Souza dos. Factors associated with drug-resistant tuberculosis in the privacy of the freedom population in the state of Paraná. 2022. Master's Dissertation - Universidade de São Paulo (USP). Escola de Enfermagem de Ribeirão Preto (PCARP/BC) Ribeirão Preto.