Analysis of the biliary MICRObiota in hepatoBILIOpancreatic diseases compared to healthy people [MICROBILIO]

• Grant number: 20/08328-9
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: April 01, 2021
• End date: March 31, 2023
• Field of knowledge: Health Sciences - Medicine - Surgery
• Principal Investigator: Alberto Luiz Monteiro Meyer
• Grantee: Milena Oliveira Suzuki
• Host Institution: Faculdade de Medicina (FM). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

The performance of the microbiota is observed in all clinical and pathological stages of carcinogenesis, since its development, diagnosis and treatment, including prognosis and survival. However, it was found that there is a scarcity of studies on biliary microbiota and its relationship with hepatobiliopancreatic diseases. Therefore, further investigation is necessary, since reaching the biliary microbiota may suggest ways for studies of biomarkers, diagnoses, tests and therapies in hepatobiliopancreatic diseases. For this, bile samples will be collected in cases and controls patients to characterize the microbiota and its variations according to the disease.

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

DE MATTOS, VITORIA CARNEIRO; NASCIMENTO, FERNANDA SAYURI DO; SUZUKI, MILENA OLIVEIRA; TABA, JOAO VICTOR; PIPEK, LEONARDO ZUMERKORN; MORAES, WALTER AUGUSTO FABIO; CORTEZ, VITOR SANTOS; KUBRUSLY, MARCIA SALDANHA; TORSANI, MATHEUS BELLONI; IUAMOTO, LEANDRO; et al. MICRObiota on BILIOpancreatic malignant diseases [MICROBILIO]: A systematic review. Clinics, v. 77, p. 13-pg., 2022-01-01. (20/08330-3, 20/08328-9)