Composition-structure-property correlations in boroncontaining bioglasses, elucidated by solid state nuclear magnetic resonance

• Grant number: 21/06370-0
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• Effective date (Start): August 01, 2021
• Effective date (End): May 15, 2023
• Field of knowledge: Physical Sciences and Mathematics - Physics - Condensed Matter Physics
• Principal Investigator: Hellmut Eckert
• Grantee: Anuraag Gaddam
• Host Institution: Instituto de Física de São Carlos (IFSC). Universidade de São Paulo (USP). São Carlos , SP, Brazil
• Associated research grant: 13/07793-6 - CEPIV - Center for Teaching, Research and Innovation in Glass, AP.CEPID

Abstract

The incorporation of boron into bioglasses has recently attracted interest owing to increased bioactivity, improved biocompatibility and antibacterial function. In addition, borate formulations serve to enhance the mechanical stability of bioglasses. Despite this considerable interest, to the present date no information is available regarding the chemical nature of the borate species and its structural integration in the bioglass network. The present proposal addresses this issue using advanced solid state Nuclear Magnetic Resonance (NMR) techniques in a number of standard bioglass formulations such as the 45S5 and the biosilicate (Na2O-CaO-SiO2-P2O5) systems prepared either by melt-cooling or by the sol-gel method. In parallel, the bioactivity will be tested by measuring the calcium, boron and phosphorus dissolution kinetics of these glasses in simulated body fluid, and the formation of hydroxyapatite carbonate will be monitored using attenuated reflectance infrared spectroscopy and NMR spectroscopy of recovered samples. (AU)

Scientific publications

(6)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

KESHRI, SHWETA R.; MANDAL, INDRAJEET; GANISETTI, SUDHEER; KASIMUTHUMANIYAN, S.; KUMAR, RAJESH; GADDAM, ANURAAG; SHELKE, ANKITA; AJITHKUMAR, THALASSERIL G.; GOSVAMI, NITYA NAND; KRISHNAN, N. M. ANOOP; et al. Elucidating the influence of structure and Ag+ -Na+ ion-exchange on crack-resistance and ionic conductivity of Na3Al1.8Si1.65 P-1.8 O-12 glass electrolyte. ACTA MATERIALIA, v. 227, p. 12-pg., 2022-04-01. (13/07793-6, 21/06370-0)

BRADTMUELLER, HENRIK; GADDAM, ANURAAG; ECKERT, HELLMUT; ZANOTTO, EDGAR D.. Structural rearrangements during sub- T g relaxation and nucleation in lithium disilicate glass revealed by a solid-state NMR and MD strategy. ACTA MATERIALIA, v. 240, p. 13-pg., 2022-11-01. (13/07793-6, 19/26399-3, 21/06370-0)

BENTO, RICARDO; GADDAM, ANURAAG; OSKOEI, PARASTU; OLIVEIRA, HELENA; FERREIRA, JOSE M. F.. 3D Printing of Macro Porous Sol-Gel Derived Bioactive Glass Scaffolds and Assessment of Biological Response. MATERIALS, v. 14, n. 20, OCT 2021. (21/06370-0, 13/07793-6)

MATURI, FERNANDO E. E.; GADDAM, ANURAAG; BRITES, CARLOS D. S.; SOUZA, JOACILIA M. M.; ECKERT, HELLMUT; RIBEIRO, SIDNEY J. L.; CARLOS, LUIÏS D.; MANZANI, DANILO. Extending the Palette of Luminescent Primary Thermometers: Yb³⁺/Pr³⁺ Co-Doped Fluoride Phosphate Glasses. CHEMISTRY OF MATERIALS, v. 35, n. 17, p. 10-pg., 2023-08-02. (13/07793-6, 21/06370-0)

JAGANNATH, G.; GADDAM, ANURAAG; RAO, S. VENUGOPAL; AGARKOV, D. A.; KORABLEVA, G. M.; GHOSH, MANASI; DEY, KRISHNA KISHOR; FERREIRA, JOSE M. F.; ALLU, AMARNATH R.. Tunable femtosecond nonlinear absorption and optical limiting thresholds of La2O3-B2O3 glasses by controlling the borate structural units. SCRIPTA MATERIALIA, v. 211, p. 8-pg., 2022-04-01. (13/07793-6, 21/06370-0)

BRADTMUELLER, HENRIK; ZHENG, QIUJU; GADDAM, ANURAAG; ECKERT, HELLMUT; ZANOTTO, EDGAR D.. Structural impact of niobium oxide on lithium silicate glasses: Results from advanced interaction-selective solid-state nuclear magnetic resonance and Raman spectroscopy. ACTA MATERIALIA, v. 255, p. 15-pg., 2023-06-10. (19/26399-3, 13/07793-6, 21/06370-0)