Synthesis of Iminophosphoranes from nitroarenes by an electrochemical approach

• Grant number: 21/09145-8
• Support Opportunities: Scholarships abroad - Research Internship - Doctorate
• Start date: December 01, 2021
• End date: November 30, 2022
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Organic Chemistry
• Principal Investigator: Kleber Thiago de Oliveira
• Grantee: Rodrigo Costa e Silva
• Supervisor: Timothy Noel
• Host Institution: Centro de Ciências Exatas e de Tecnologia (CCET). Universidade Federal de São Carlos (UFSCAR). São Carlos , SP, Brazil
• Institution abroad: University of Amsterdam (UvA), Netherlands
• Associated to the scholarship: 18/00879-6 - Arylation reactions of heterocycles photocatalysed by porphyrins in both batch and continuous flow conditions., BP.DR

Abstract

The iminophosphoranes are important building blocks for C-N bonds formation, such as the aza-Wittig reaction and other relevant organic transformations. Herein, we propose to study the conversion of nitroarenes and triphenylphosphine to the correspondent iminophosphoranes via an electrochemistry approach. Subsequent studies involving photoelectrochemistry are also aimed at both batch and continuous flow conditions. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

SANJOSE-ORDUNA, JESUS; SILVA, RODRIGO C.; RAYMENANTS, FABIAN; REUS, BENTE; THAENS, JANNIK; DE OLIVEIRA, KLEBER T.; NOEL, TIMOTHY. Dual role of benzophenone enables a fast and scalable C-4 selective alkylation of pyridines in flow. CHEMICAL SCIENCE, v. 13, n. 42, p. 6-pg., 2022-10-10. (21/09145-8)

COSTA E SILVA, RODRIGO; VEGA, CLARA; REGNIER, MORGAN; CAPALDO, LUCA; WESENBERG, LARS; LOWE, GRACE; DE OLIVEIRA, KLEBER THIAGO; NOEL, TIMOTHY. Electrosynthesis of Aryliminophosphoranes in Continuous Flow. ADVANCED SYNTHESIS & CATALYSIS, v. N/A, p. 7-pg., 2023-08-09. (18/00879-6, 20/06874-6, 21/09145-8)