Optimization of the processes for extraction and physicochemical characterization of extracts from Tetragonisca angustula (Jataí) propolis for drug delivery systems development

• Grant number: 21/12891-3
• Support Opportunities: Scholarships abroad - Research Internship - Scientific Initiation
• Start date: February 01, 2022
• End date: April 01, 2022
• Field of knowledge: Interdisciplinary Subjects
• Principal Investigator: Patricia Targon Campana
• Grantee: Natália Cristina Pinto Vieira
• Supervisor: Roger Clive Hiorns
• Host Institution: Escola de Artes, Ciências e Humanidades (EACH). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Institution abroad: Institut des Sciences Analytiques et de Physico-Chimie pour l’Environnement et les Matériaux (IPREM), France
• Associated to the scholarship: 20/09435-3 - Absorption and fluorescence spectroscopies studies of nanocomposites formation from Jataí bee propolis (Tetragonisca angustula) and nano-clay haloisite for drug delivery systems, BP.IC

Abstract

In this project, the extraction process of propolis from the stingless bee Tetragonisca angustula (Jataí) will be improved, several different solvents will be tested, and the optimized extracts will be characterised by physicochemical techniques as thermal analysis and chromatography. Photophysical characterization of obtained propolis extracts, as well as its coumarins, curcumins, and flavonoids, under different conditions, will be performed through the electronic and vibrational absorbance. The different states of aggregation, and charge interactions will be studied by modelling. The fully characterised propolis will be used, in the future, for the development of controlled release systems of their bioactive constituents. (AU)