Surface characterization and microbiological analysis of titanium dental implants after application of plasma electrolytic oxidation coatings

• Grant number: 21/11780-3
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: January 01, 2022
• End date: December 31, 2022
• Field of knowledge: Health Sciences - Dentistry - Dental Materials
• Principal Investigator: Cássio Do Nascimento
• Grantee: Thales Peres Candido Moreira
• Host Institution: Faculdade de Odontologia de Ribeirão Preto (FORP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil

Abstract

Peri-implant inflammatory reactions are commonly found in the presence of microbial biofilm disruption. Although the success and survival rates of dental implants range from values of up to 90%, the occurrence of inflammatory reaction may result in implant failure. Ceramic substrates seem to present lower susceptibility to bacterial adhesion and colonization by periodontal pathogenic species. The modification of titanium implant surfaces by either conventional plasma electrolytic oxidation (PEO) or by PEO followed by the addition of ions with antimicrobial effects may contribute to minimizing the adhesion and growth of bacterial species on the dental implants, reducing the risks of peri-implant tissues infections. In this research protocol, we propose an interdisciplinary approach associating surface characterization and microbiological analysis investigating the impact of novel titanium implant surface coated by the ceramic film on the microbiota of peri-implant sites. Microbiological outcomes will be investigated using an animal model study with rodents.(AU)