Synthesis of guanidine derivatives exhibiting potential biological activities

• Grant number: 22/01750-2
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• Start date: May 01, 2022
• End date: April 30, 2026
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Organic Chemistry
• Principal Investigator: Igor Dias Jurberg
• Grantee: Tales Antonio Camargo Goulart
• Host Institution: Instituto de Química (IQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
• Associated research grant: 19/17721-9 - The role of Chemistry in holobiont adaptation, AP.TEM
• Associated scholarship(s): 23/13225-2 - Preparation of Agelastatin Alkaloids and Evaluation of their Anticancer Activity against Brain Tumors, BE.EP.PD

Abstract

This project aims at the synthesis of a variety of guanidines containing several levels of complexity, inspired in structures of natural products. This project represents a part of the Thematic Project of Fapesp entitled "The Role of Chemistry in Holobiont Adaptation" (2019/17721-9). (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

GALLO, RAFAEL D. C.; CARIELLO, GUILHERME; GOULART, TALES A. C.; JURBERG, IGOR D.. Visible light-mediated photolysis of organic molecules: the case study of diazo compounds. CHEMICAL COMMUNICATIONS, v. 59, n. 48, p. 15-pg., 2023-05-11. (22/01104-3, 20/00144-6, 22/01750-2, 19/17721-9)

CAPELLARO, KAUE C.; GOULART, TALES A. C.; GALLO, RAFAEL D. C.; DE S. SCHENFEL, JULIANA; JURBERG, IGOR D.. Friedel-Crafts-Type Arylation Strategy for the Conversion of Alkyl 2-((Diphenoxyphosphoryl)oxy)-2-arylacetates to α,α-Diaryl Esters. ACS ORGANIC & INORGANIC AU, v. 4, n. 1, p. 7-pg., 2023-11-09. (19/09380-7, 20/00144-6, 22/01750-2, 22/01104-3, 19/17721-9)