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Influence of calcium cyclotriphosphate in bleaching gel formulations on the aesthetic efficacy, microhardness and roughness of dental enamel

Grant number: 22/05724-6
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Start date: July 01, 2022
End date: December 31, 2023
Field of knowledge:Health Sciences - Dentistry - Dental Materials
Principal Investigator:Alberto Carlos Botazzo Delbem
Grantee:Gabriella de Farias Batista
Host Institution: Faculdade de Odontologia (FOA). Universidade Estadual Paulista (UNESP). Campus de Araçatuba. Araçatuba , SP, Brazil

Abstract

The objective of this project will be to evaluate in vitro the effect of different concentrations (0.25%, 0.5% and 1%) of cyclotriphosphate (sodium trimetaphosphate, "TMP") with partial replacement of sodium by calcium (Ca2+) (CaNaTMP ) in bleaching formulations based on hydrogen peroxide (H2O2) at 17.5% and 35% on the change in color, microhardness and roughness of dental enamel. The bleaching gels will be applied on enamel/dentin discs from bovine teeth, according to the groups: 1) 35% H2O2; 2) 35% H2O2 + 0.25% CaNaTMP; 3) 35% H2O2 + 0.5% CaNaTMP; 4) 35% H2O2 + 1% CaNaTMP; 5) 17.5% H2O2); 6) 17.5% H2O2 + 0.25% CaNaTMP; 7) 17.5% H2O2 + 0.5% CaNaTMP; and 8) 17.5% H2O2 + 1% CaNaTMP. The gels will be applied only once, during 3 sessions of 30 minutes/session, every 7 days, totaling 21 days. Then, the color change will be evaluated by quantified reflection spectrophotometry (”E*ab , ”WID and ”E00), as well as the final surface microhardness (SHF) to calculate the percentage of surface microhardness loss (%SH) and surface roughness (Ra). Variables that present normal and homogeneous distribution will be submitted to analysis of variance (p<0.05). Otherwise, they will be submitted to the Kruskal Wallis test (p<0.05). The multiple comparison test will be Student-Newman-Keuls.

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Scientific publications
(The scientific publications listed on this page originate from the Web of Science or SciELO databases. Their authors have cited FAPESP grant or fellowship project numbers awarded to Principal Investigators or Fellowship Recipients, whether or not they are among the authors. This information is collected automatically and retrieved directly from those bibliometric databases.)
NUNES, GABRIEL PEREIRA; BATISTA, GABRIELLA DE FARIAS; DE TOLEDO, PRISCILA TONINATTO ALVES; MARTINS, TAMIRES PASSADORI; ALVES, RENATA DE OLIVEIRA; FERNANDES, ANA VITORIA PEREIRA; DELBEM, ALBERTO CARLOS BOTAZZO. Synthesis and application of calcium cyclotriphosphate in bleaching formulations: Effects on dental enamel properties. Journal of Dentistry, v. 155, p. 11-pg., . (22/05724-6)