Cellulose ether, biomass and calcium peroxide based cryogels for the removal of drugs and oxygen release in aqueous medium

• Grant number: 22/06284-0
• Support Opportunities: Scholarships in Brazil - Doctorate
• Start date: August 01, 2022
• Status: Discontinued
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Physical-Chemistry
• Principal Investigator: Denise Freitas Siqueira Petri
• Grantee: Camila Gruber Chiaregato
• Host Institution: Instituto de Química (IQ). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Associated scholarship(s): 23/18116-7 - Hierarchical structure of cellulose ether porous materials for controlled oxygen release, BE.EP.DR

Abstract

Contamination and water scarcity are current problems that demand immediate actions to conserve them. Remediation of contaminated water can be performed by adsorbing contaminants and increasing the concentration of dissolved O2 in the medium. This project aims at developing new porous materials (cryogels) capable of adsorbing drugs and releasing O2 to the environment simultaneously. The cryogels will be produced by combining hydroxypropyl methylcellulose (HPMC) or carboxymethyl cellulose (CMC), microparticles of sugarcane or Moringa oleifera bagasse and calcium peroxide (CaO2) particles coated with amphiphilic molecules. The reaction rate between CaO2 and water, resulting in the release of O2, will be determined as a function of the chemical structure of the amphiphilic molecules, pH, and temperature. Adsorption studies of caffeine, ibuprofen, and paracetamol, isolated and synthetic mixtures will be carried out in batch and column adsorption studies. The effects of pH, temperature, and O2 release on the adsorption capacity of cryogels will be investigated. The efficiency of the cryogels developed will also be evaluated in the remediation of a real laboratory waste from practical classes for undergraduate students at IQUSP. Such laboratory waste contains mainly caffeine, ibuprofen, and paracetamol. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

CHIAREGATO, CAMILA GRUBER; BERNARDINELLI, OIGRES DANIEL; SHAVANDI, AMIN; SABADINI, EDVALDO; PETRI, DENISE FREITAS SIQUEIRA. The effect of the molecular structure of hydroxypropyl methylcellulose on the states of water, wettability, and swelling properties of cryogels prepared with and without CaO2. Carbohydrate Polymers, v. 316, p. 10-pg., 2023-05-20. (18/13492-2, 22/06284-0)