Neuromodulation combined with other neurotechnologies for application in the motor rehabilitation of Stroke patients

• Grant number: 22/08057-0
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• Start date: August 01, 2022
• End date: June 30, 2026
• Field of knowledge: Interdisciplinary Subjects
• Principal Investigator: Gabriela Castellano
• Grantee: Cássio Víctora Ruas
• Host Institution: Instituto de Física Gleb Wataghin (IFGW). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
• Associated research grant: 13/07559-3 - BRAINN - The Brazilian Institute of Neuroscience and Neurotechnology, AP.CEPID

Abstract

Transcranial Direct Current Stimulation (tDCS) is a technique that promotes modulation of neural activity with direct application of low-intensity electrical current in brain target areas. tDCS has been used as a relevant intervention in the treatment of patients with neurological diseases and movement disorders. Its effects are known to potentiate sensorimotor and cognitive recovery when stimulation is combined with other therapeutic alternatives, such as the use of virtual reality and robotic therapy. In order to improve the rehabilitation of neurological patients, BRAINN is investing in the development of new technologies and in the combination of therapies. Research with the creation of exoskeletons coupled to robotic glove can be used as an assistance and rehabilitation tool for neurological patients. The combined use of exoskeleton with robotic glove and Functional Electrical Stimulation (FES) aims to favor the recovery of sensorimotor function, assist movement and promote progress in the rehabilitation process of patients with physical limitations and compromised functional capacity. In this context, the objectives of the research project to be developed together with BRAINN are to investigate the combined effects of tDCS associated with neurorehabilitation techniques (robotic devices and virtual reality tools) using fMRI and other assessment methods, and to compare the pre and post-treatment on neural activity, motor excitability, muscle electrical activity and sensorimotor function. This project is linked to the BRAINN subproject "Study and development of assistive and rehabilitation technologies for neurological patients", coordinated by Prof. Gabriela Castellano. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

CARLOS, BRUNA M.; MENEZES, LUCAS T.; ROSA, BEATRIZ; FURUMOTO, BRUNA F.; FEITOSA, SAULO S.; FERNANDES, CORINA A.; FERREIRA-MELO, SILVIA E.; PEREIRA, JULIA D.; ALMEIDA, SARA; BRANDAO, ALEXANDRE F.; et al. Graph network and symmetry analysis after combined XR and tDCS in stroke. Biomedical Signal Processing and Control, v. 96, p. 9-pg., 2024-06-05. (15/03695-5, 13/07559-3, 20/16571-0, 22/08057-0)

CARLOS, BRUNA M.; MENEZES, LUCAS T.; DE VAZQUEZ, PEDRO FELIPE G.; FEITOSA, SAULO S.; PEREIRA, JULIA D.; PONTES, LARISSA L.; ALMEIDA, SARA R. M.; RUAS, CASSIO, V; CASTELLANO, GABRIELA. Brain symmetry index correlates with time after stroke and lower limb function. 2024 20TH INTERNATIONAL SYMPOSIUM ON MEDICAL INFORMATION PROCESSING AND ANALYSIS, SIPAIM 2024, v. N/A, p. 4-pg., 2024-01-01. (20/16571-0, 22/08057-0, 23/11024-0, 15/03695-5, 13/07559-3)

RUAS, CASSIO V.; RATEL, SEBASTIEN; NOSAKA, KAZUNORI; CASTELLANO, GABRIELA; PINTO, RONEI S.. Resistance training effects on pubertal children with a risk of developing pediatric dynapenia. EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY, v. 124, n. 7, p. 15-pg., 2024-02-29. (22/08057-0)