Postprandial responses to fish ingestion: in vivo and in vitro study

• Grant number: 22/07805-3
• Support Opportunities: Scholarships in Brazil - Doctorate
• Start date: April 01, 2023
• End date: November 30, 2026
• Field of knowledge: Health Sciences - Nutrition
• Principal Investigator: Jarlei Fiamoncini
• Grantee: Leandro da Silva Presenza
• Host Institution: Faculdade de Ciências Farmacêuticas (FCF). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Associated research grant: 13/07914-8 - FoRC - Food Research Center, AP.CEPID

Abstract

Fish consumption has increased in recent decades, due to consumer interest in the positive health effects associated with the regular intake of this food, among other factors. Previous studies have described significant results in the acute consumption of fish products, favoring the reduction of triglycerides, total cholesterol, low-density lipoprotein, reduced insulin secretion, and increased plasma concentration of high-density lipoprotein in the postprandial. Despite this scenario, there are still few studies investigating acute metabolic responses, such as postprandial physiological phenomena after consumption of the main ichthyic species ingested by Brazilians. Considering that the protein composition and digestibility of fish are different compared to other protein sources regularly consumed in the diet, such as beef, it is expected that postprandial responses to fish consumption will also be different. The investigation of the acute effects of fish intake on postprandial metabolism may reveal new beneficial effects associated with this food group, which could be added to the chronic nutritional benefits already reported. The present proposal compares the acute effects of the ingestion of two sources of fish protein and bovine origin on postprandial metabolism. It is expected to generate new data on postprandial physiology and investigate possible effects of fish intake that could contribute to public health management and healthy dietary patterns.