| Grant number: | 23/04057-9 |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |
| Start date: | July 01, 2023 |
| End date: | June 30, 2026 |
| Field of knowledge: | Engineering - Biomedical Engineering - Medical Engineering |
| Principal Investigator: | Theo Zeferino Pavan |
| Grantee: | David Alejandro Collazos Burbano |
| Host Institution: | Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto (FFCLRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil |
| Associated research grant: | 21/06728-2 - Photoacoustic and ultrasound imaging for theranostic purposes, AP.JP2 |
Abstract Magnetic nanoparticles (MNPs) have shown great potential in biomedicine for diagnostic and therapeutic purposes; however, their visualization using ultrasound is limited by poor contrast. Photoacoustic imaging and magnetomotive ultrasound (MMUS) have been studied to overcome this limitation. This project aims to improve visualization of MNPs by combining photoacoustic and MMUS techniques, which is expected to improve image specificity and signal-to-noise ratio. The proposed method will be evaluated using phantoms and murine tumor models, and involves inducing localized vibrations to MNP-laden regions using magnetomotive force to eliminate clutter noise. The study will develop a method to simultaneously generate photoacoustic and MMUS images for improved detection of magnetic NPs. | |
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