Development of lanthanide-doped persistent luminescence perovskite oxide nanoparticles for bioimaging and security labeling

• Grant number: 23/05351-8
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• Start date: October 01, 2023
• Status: Discontinued
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Inorganic Chemistry
• Principal Investigator: Rogéria Rocha Gonçalves
• Grantee: York Estewin Serge Correales
• Host Institution: Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto (FFCLRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
• Associated research grant: 21/08111-2 - Development of rare earth based light converters: luminescent markers, optical sensors, and amplifiers, AP.TEM
• Associated scholarship(s): 24/17123-2 - Exploring Nanothermometry in the NIR-II Region and Hyperspectral Bioimaging with Lanthanide-Based Nanomaterials, BE.EP.PD

Abstract

Due to the increasing demand for both efficient luminescent markers for disease diagnosis using bioimaging detection and luminescence-based anti-counterfeiting tools, the development of new luminescence materials, especially those with persistent luminescence (PeL) properties, is of great interest due to their long-lasting post-excitation emission, which improves detection as a result of the high luminescence signal-to-noise ratio and low background autofluorescence of the tissue or medium.Lanthanide-doped PeL perovskite oxides emerge as promising materials due to the combination of the structural, electronic, and luminescent characteristics of perovskites, with the numerous advantages offered by lanthanide ions, such as narrow and tunable emission in a wide range of the electromagnetic spectrum (ultraviolet, visible and near infrared), long excited state lifetimes, long luminescence decays, among others, which makes them suitable for applications in energy production/collection, safety labeling, and biological and medical fields.This project proposes the development of lanthanide-doped PeL perovskite oxides for applications in bioimaging and security labeling, addressing fundamental limitations that generally restrict the practical application of oxide materials, such as the lack of precise control over particle size/distribution and their poor water dispersibility and/or limited colloidal stability required for certain applications. (AU)