Preparation of Agelastatin Alkaloids and Evaluation of their Anticancer Activity against Brain Tumors

• Grant number: 23/13225-2
• Support Opportunities: Scholarships abroad - Research Internship - Post-doctor
• Start date: June 01, 2024
• End date: May 31, 2025
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Organic Chemistry
• Principal Investigator: Igor Dias Jurberg
• Grantee: Tales Antonio Camargo Goulart
• Supervisor: Daniel Romo
• Host Institution: Instituto de Química (IQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
• Institution abroad: Baylor University, United States
• Associated to the scholarship: 22/01750-2 - Synthesis of guanidine derivatives exhibiting potential biological activities, BP.PD

Abstract

This project has as its main objective the synthesis of agelastatin derivatives and investigation of their anticancer activity against brain tumors. The project will be developed in partnership with researchers from Texas State University and the University of Pittsburgh (USA).