Determnation of quality of life of patients with familial hypercholesterolemia (FH)

• Grant number: 24/07097-4
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: June 01, 2024
• End date: May 31, 2025
• Field of knowledge: Health Sciences - Medicine - Medical Clinics
• Principal Investigator: Maria Cristina de Oliveira Izar
• Grantee: Leandro Alcantara Barros
• Host Institution: Escola Paulista de Medicina (EPM). Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. São Paulo , SP, Brazil

Abstract

Familial hypercholesterolemia (FH) is a codominant genetic disorder that has an important association with premature atherosclerotic cardiovascular disease (ASCVD), thus contributing to the occurrence of acute myocardial infarction, aortic stenosis, peripheral arterial disease and stroke. In the biopsychosocial context, this disease possesses a relationship with decrease in quality of life if not treated adequately, leading to reduction on physical and mental health, and of life expectancy. The literature is scarce in Brazil regarding the correlation between Familial Hypercholesterolemia and parameters of quality of life, and the present study has the objective to bring to life these aspects, addressing questions on how these patients feel in the context of physical and mental health, social and environment interrelationship, and trying to understand the factors that contribute to better or worse quality of life. In addition, the data collected will contribute to the Brazilian Registry of Familial Hypercholesterolemia.