Artificial Intelligence platform for the research and development of multi-target drugs for the treatment of Neglected Diseases

• Grant number: 24/14836-8
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• Start date: October 01, 2024
• End date: September 30, 2025
• Field of knowledge: Health Sciences - Pharmacy
• Principal Investigator: Altigran Soares da Silva
• Grantee: Tallita Marques Machado
• Host Institution: Instituto de Computação. Universidade Federal do Amazonas (UFAM). Ministério da Educação (Brasil). Manaus , SP, Brazil
• Company: Universidade Federal de Minas Gerais (UFMG). Instituto de Ciências Exatas (ICEx)
• Associated research grant: 20/09866-4 - Artificial Intelligence Innovation Center for Health (CIIA-Health), AP.PCPE

Abstract

Neglected diseases represent a significant burden on global health, primarily affecting populations in developing countries. The lack of investment in research and development of new drugs for these diseases makes the search for innovative and efficient solutions crucial. Artificial intelligence (AI) emerges as a powerful tool to accelerate and optimize the drug discovery process, opening doors to new therapies. Therefore, this project proposes to develop a platform applying AI and molecular modeling techniques with the aim of facilitating and speeding up the development of drugs for neglected diseases. To this end, the development and standardization of the system will be carried out, as well as the application of validation processes and comparative analyzes to verify operational functioning with a view to verifying the veracity of the information generated.