Insecticide-impregnated nets with alphacypermethrin and chlorfenapyr: evaluations of biological parameters of Triatoma infestans adults (Reduviidae:Triatominae) after contact

• Grant number: 24/10936-8
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: September 01, 2024
• Status: Discontinued
• Field of knowledge: Biological Sciences - Parasitology - Entomology and Malacology of Parasites and Vectors
• Principal Investigator: Mara Cristina Pinto
• Grantee: Guilherme Wagner Teles Lima
• Host Institution: Faculdade de Ciências Farmacêuticas (FCFAR). Universidade Estadual Paulista (UNESP). Campus de Araraquara. Araraquara , SP, Brazil
• Associated scholarship(s): 25/05977-0 - Inseticide-impregnated bednets with alpha-cypermethrin and chlorfenapyr: evaluation of biological parameters of adults of Triatoma infestans (Reduviidae: Triatominae) after contact., BE.EP.IC

Abstract

American trypanosomiasis, also known as Chagas disease, is a potentially fatal disease caused by the protozoan parasite Trypanosoma cruzi. The World Health Organization (WHO) reinforces the need to improve early diagnosis and interruption of transmission, considering the annual record of around 40 thousand new cases and 12 thousand deaths. The governmental epidemiological surveillance seeks to reduce mortality and morbidity rates through combating the vectors of the etiological agent of this zoonosis, namely triatomines, species of hematophagous insects belonging to the family Reduviidae and subfamily Triatominae. In this sense, aiming to reduce the contact between triatomines and humans, the use of insecticide-impregnated mosquito nets has been considered in areas where Chagas disease is transmitted. Currently the Interceptor® mosquito net, impregnated with alphacypermethrin, is used in Brazil in areas where malaria is endemic, with the aim of containing the transmission of the disease, by reducing the contact with culicidae. However, this product will soon be replaced by the Interceptor G2®, impregnated with alphacypermethrin and chlorfenapyr. Considering the existence of endemic regions where malaria and Chagas disease overlap, it is epidemiologically interesting to evaluate the impact of this mosquito net in triatomines. The triatomine species Triatoma infestans stands out as a vector of T. cruzi, the etiological agent of Chagas disease, and has a wide distribution in South America. Therefore, the objective of this work will be to evaluate mortality and biological parameters such as feeding and oviposition of T. infestans after different times of exposure to the Interceptor G2® mosquito net.