Incidence of Frailty Syndrome in the Brazilian community-dwelling older adults

• Grant number: 24/02136-1
• Support Opportunities: Scholarships in Brazil - Doctorate
• Start date: October 01, 2024
• End date: September 30, 2026
• Field of knowledge: Health Sciences - Physiotherapy and Occupational Therapy
• Principal Investigator: Ruth Caldeira de Melo
• Grantee: Giselle Layse Andrade Buarque Santos
• Host Institution: Faculdade de Ciências Médicas (FCM). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil

Abstract

The epidemiological literature on frailty in the Brazilian context often highlights prevalence to the detriment of incidence. However, an in-depth understanding of its incidence is essential to assess the temporal dynamics of the syndrome and its impact, as well as to identify risk factors anddevelop appropriate preventive strategies. Objective: To analyze the scientific evidence related to the incidence of frailty syndrome in Brazil and the factors associated with its incidence in a sample of community-dwelling older adults. Methods: divided into two studies: 1) systematic review andmeta-analysis. The search will be carried out in eight databases, including publications in English, Portuguese and Spanish. Inclusion criteria will be based on the mnemonic "CoCoPop" (frailty status,community context and individuals aged e 60 years). The selection of studies will be carried out by two independent reviewers and disagreements will be resolved by a third reviewer. The quality of the studies will be assessed using the JBI tool. The selection of studies will be presented in the PRISMA flowchart and the data will be presented in tables and charts. The data will be meta-analyzed to calculate the pooled incidence; 2) longitudinal study. This involves investigating the incidence of frailty in a cohort of 549 older adults living in urban areas of Campinas and the Ermelino Matarazzo subdistrict, who participated in the 2008-2009 and 2016-2017 waves of the Fibra Study. Variables of interest include:sociodemographic information, frailty status, self-rated health, cognitive impairment, perceived social support and advanced activities of daily living. The incidence of frailty and pre-frailty in the second wave will be calculated relative to the number of non-cases at baseline. Association tests between variables (Pearson and McNema chi-square) will be used, in addition to the analysis of risk factors for the incidence of frailty and pre-frailty (Poisson regression). A significance level of p<0.05 will be adopted. (AU)