DETERMINATION OF THE COMPOSITION OF THE NASAL MICROBIOTA AND SUBGLOTIC AREA IN BRACHYCEPHALIC DOGS OF THE FRENCH BULLDOG BREED WHETHER OR NOT AFFECTED BY BRACHYCEPHALIC AIR OBSTRUCTIVE SYNDROME (SOAB)

• Grant number: 23/18069-9
• Support Opportunities: Scholarships in Brazil - Master
• Start date: December 01, 2024
• Status: Discontinued
• Field of knowledge: Agronomical Sciences - Veterinary Medicine - Animal Clinics and Surgery
• Principal Investigator: Paola Castro Moraes
• Grantee: Herlem Camila Pinto da Silva
• Host Institution: Faculdade de Ciências Agrárias e Veterinárias (FCAV). Universidade Estadual Paulista (UNESP). Campus de Jaboticabal. Jaboticabal , SP, Brazil
• Associated scholarship(s): 25/01611-0 - ASSESSMENT OF MICROBIOTA COMPOSITION IN THE NOSTRILS AND SUBGLOTTIC AREA OF BRACHYCEPHALIC DOGS WITH AND WITHOUT BRACHYCEPHALIC OBSTRUCTIVE AIRWAY SYNDROME (BOAS), BE.EP.MS

Abstract

Considering that brachycephalic dogs have been increasing in popularity amongfamilies over the years and due to their anatomical deformities have apredisposition to the development of Brachycephalic Air Obstructive Syndrome (BOAS) whichcauses several consequences for the body due to the inflammation generated and changes inmicrobiota, reducing the animal's quality of life, this study proposes the determination andcomparison of the composition of the nasal microbiota and subglottic area in 20 Bulldog dogsFrench affected (grade III) or unaffected (grade 0) by BOAS, through metagenomic analysisof the nasal microbiota and subglottic area, with the aim of determining and comparing the diversitytaxonomic analysis of microorganisms from affected (grade III) and non-affected French Bulldogs(grade 0) by SOAB and correlate the prevalence of certain taxonomic groups, throughof shotgun sequencing.