Graphene Oxide Functionalized with Ionic Liquids for monitoring Triazines and Carbamates in Spanish Wines by Microextraction by packed sorbent (MEPS)

• Grant number: 24/12325-6
• Support Opportunities: Scholarships abroad - Research Internship - Doctorate
• Start date: March 05, 2025
• End date: August 31, 2025
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Analytical Chemistry
• Principal Investigator: Fernando Mauro Lanças
• Grantee: Alessandra Timóteo Cardoso
• Supervisor: Alejandro Cifuentes
• Host Institution: Instituto de Química de São Carlos (IQSC). Universidade de São Paulo (USP). São Carlos , SP, Brazil
• Institution abroad: Universidad Autónoma de Madrid (UAM), Spain
• Associated to the scholarship: 23/06258-1 - Development, characterization, evaluation and applications of graphene oxide modified with ionic liquids, BP.DR

Abstract

Viticulture has witnessed significant global growth, with Spain leading in vineyard cultivation. However, the prevalent use of pesticides to control potential losses in wine grape production due to pests, fungal growth, weeds, or insects persists. Despite regulation by the European Commission for maximum residue limits (MRL), pesticide residues and their metabolites can still contaminate the final product, raising public health concerns for consumers. There is a growing demand for monitoring emerging pesticides, such as carbamates and triazines, in vineyard products reaching consumers. Developing analytical methods to monitor these pesticides in wine and ensure food safety is a crucial area of study. Therefore, the primary focus of this project is the development of a hybrid extraction sorbent based on the functionalization of graphene oxide (G.O.) with ionic liquids (I.L.s). This sorbent should promote multiple interaction mechanisms with the analytes for application in microextraction by packed sorbent (MEPS) extraction of selected pesticides from the carbamate and triazine classes in Spanish-origin wines, with subsequent analysis by LC-MS/MS. Nevertheless, its application in miniaturized extraction techniques such as MEPS strongly aligns with the principles of green analytical chemistry (GAC) because it minimizes the amount of sample and organic solvents used and enables the sorbent to be reused, consequently reducing organic waste generated compared to conventional extraction methods.