Assessment of Platelet Aggregation Using PLATELETWORKS® in Patients with Previous Myocardial Infarction with and without Concomitant Peripheral Arterial Disease

• Grant number: 24/15903-0
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: October 01, 2024
• End date: September 30, 2025
• Field of knowledge: Health Sciences - Medicine - Medical Clinics
• Principal Investigator: José Carlos Nicolau
• Grantee: Luis Fernando Lorga Salis
• Host Institution: Instituto do Coração Professor Euryclides de Jesus Zerbini (INCOR). Hospital das Clínicas da Faculdade de Medicina da USP (HCFMUSP). Secretaria da Saúde (São Paulo - Estado). São Paulo , SP, Brazil
• Associated research grant: 23/10447-4 - Platelet aggregation: new therapeutic interventions, mechanisms and evaluation methods, with focus on high social impact diseases, AP.TEM

Abstract

The concurrent presence of peripheral arterial disease (PAD) and acute myocardial infarction (AMI) increases the risk of thrombotic events and worse clinical outcomes. Studies indicate that platelet aggregation is elevated in patients with PAD, which may be related to the severity of the disease. However, there are no studies that have specifically analyzed platelet aggregation in patients with a prior AMI with and without the presence of PAD