MONITORING OF PARAMETERS IN CATS SUBJECTING TO PRESSURE-CONTROLLED MECHANICAL VENTILATION DURING SURGICAL PROCEDURES: CLINICAL STUDY.

• Grant number: 24/20605-9
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: March 01, 2025
• End date: February 28, 2026
• Field of knowledge: Agronomical Sciences - Veterinary Medicine
• Principal Investigator: Aline Magalhães Ambrósio
• Grantee: Alice Silva Alvarenga
• Host Institution: Faculdade de Medicina Veterinária e Zootecnia (FMVZ). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

In surgical interventions, general anesthesia and sedation scenarios,mechanical ventilation (MV) becomes essential for adequate gas exchange and blood oxygenation. Its importance also extends to intensive care, especially in situations of respiratory fatigue, hypoventilation, hypovolemia and circulatory shock. At the same time, the population of domestic cats has increased every year, accompanied by the advancement of feline medicine, which is at its peak on the global scene. As a result, the number of cats in hospitals and veterinary ICUs, as well as the number of surgeries performed on these animals, has increased, making MV an essential ventilatory support in several situations and participating actively and constantly in maintaining the patientns life. Despite this, there are no clinical studies in the scientific literature that address the best strategy to be used during mechanical ventilation in cats. Therefore, this study aims to collect data on ventilatory mechanics obtained by domestic felines during pressure-controlled mechanical ventilation. In addition, it will also monitor the cardiovascular and blood gas aspects of animals under anesthesia during surgical procedures. For this purpose, healthy cats between 6 months and 5 years of age will be used. Data collection will allow a deeper undertanding of the respiratory physiology of cats and will support future research in the area, contributing to safer and more affective practices in mechanical ventilation in small animals.