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Modeling of congenital disease caused by the Zika virus in the central nervous system (CNS) using 2D/3D models. The initial objective, in addition to studying the Zika virus, was expanded to include aspects related to the SARS-CoV-2 coronavirus.

Grant number: 25/01199-2
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Start date: March 01, 2025
End date: February 28, 2026
Field of knowledge:Interdisciplinary Subjects
Principal Investigator:Paola Marcella Camargo Minoprio
Grantee:Sávio di Stasi Zanon
Host Institution: Institut Pasteur de São Paulo (IPSP). São Paulo , SP, Brazil
Associated research grant:17/27131-9 - Integrated strategy for the study of infectious agents causing emerging and/or neglected diseases transmitted by vectors of global impact, AP.TEM

Abstract

The neurological aspects of the Congenital Syndrome caused by the Zika virus will be modeled and investigated in vitro, using fluorescent and bioluminescent viral strains as well as neural cells derived from iPSCs.

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