Oxidation of sulfides to sulfones using iron-based biomimetic systems

• Grant number: 24/20796-9
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: May 01, 2025
• End date: April 30, 2026
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Organic Chemistry
• Principal Investigator: Emílio Carlos de Lucca Júnior
• Grantee: Anna Beatriz Facundo e Silva
• Host Institution: Instituto de Química (IQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
• Associated research grant: 24/11730-4 - Selective and late-stage functionalization of C-H bonds of complex molecules, AP.R

Abstract

Sulfones are functional groups present in several fields of application. However, although there are several methodologies for oxidizing sulfides to sulfones, each of them has limitations, such as excess of oxidizing agent, high temperatures, long reaction times, high toxicity and problems with scalability. Therefore, in this work we propose an alternative methodology using iron-based catalysis for the oxidation of sulfides to sulfones in a biomimetic manner.