Platelet Aggregation Assessment by PlateletWorks® in Patients with Non-Small Cell Lung Cancer.

• Grant number: 25/01571-9
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: April 01, 2025
• End date: March 31, 2026
• Field of knowledge: Health Sciences - Medicine - Medical Clinics
• Principal Investigator: José Carlos Nicolau
• Grantee: Beatriz Evarini
• Host Institution: Instituto do Coração Professor Euryclides de Jesus Zerbini (INCOR). Hospital das Clínicas da Faculdade de Medicina da USP (HCFMUSP). Secretaria da Saúde (São Paulo - Estado). São Paulo , SP, Brazil
• Associated research grant: 23/10447-4 - Platelet aggregation: new therapeutic interventions, mechanisms and evaluation methods, with focus on high social impact diseases, AP.TEM

Abstract

Lung cancer is a malignant disease with high morbidity and mortality. Patients with lung cancer are at increased risk of developing venous thromboembolism (VTE), due to factors related to the tumor itself, such as the release of pro-coagulant substances. Platelet aggregation plays a crucial role in thrombus formation during thromboembolic events. Platelet Works is a method used to assess platelet function, providing important information about platelet aggregation in patients with high risk of VTE and lung cancer.