Structural study of protein films deposited on quartz plates

• Grant number: 25/05096-3
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: June 01, 2025
• End date: May 31, 2026
• Field of knowledge: Physical Sciences and Mathematics - Physics - Atomic and Molecular Physics
• Principal Investigator: Jose Luiz de Souza Lopes
• Grantee: Gustavo Gimenez dos Santos Figueira
• Host Institution: Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto (FFCLRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
• Associated research grant: 22/01951-8 - Study of the chemical and structural integrity of virus-like particles and their incorporation into ordered mesoporous silica, AP.PNGP.PI

Abstract

In this project, we aim to implement the use of the spectroscopy Circular Dichroism to investigate the secondary structure of proteins deposited on the surface of Suprasil-quartz plates in the form of semi-dehydrated films. We intend to promote different functionalizations on these plates and observe the effect on the protein structure when they adsorb onto them, using circular dichroism and infrared (FT-IR). (AU)