Impact of Obstructive Sleep Apnea on the neurocognitive, behavioral, and academic development of children undergoing orthodontic treatment for Class II, Division 1 Malocclusion

• Grant number: 25/01229-9
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: July 01, 2025
• End date: December 31, 2025
• Field of knowledge: Health Sciences - Dentistry - Orthodontics
• Principal Investigator: Ana Cláudia de Castro Ferreira Conti
• Grantee: Mariana Rosolen Gomes
• Host Institution: Faculdade de Odontologia de Bauru (FOB). Universidade de São Paulo (USP). Bauru , SP, Brazil

Abstract

Introduction: Diagnosed children with Obstructive Sleep Apnea (OSA) mayexperience impaired neurocognitive functions if left untreated, impacting their qualityof life as well as their academic and social development. Objective: This study aimsto analyze the impact of OSA on the neurocognitive, behavioral, and academicdevelopment of children with Class II, division 1 malocclusion and OSA who undergoorthopedic treatment with maxillary expansion and mandibular advancement.Materials and Methods: This research is part of an ongoing crossover RandomizedClinical Trial, currently under review by FAPESP under process number 2023/14203-2. The sample will consist of 20 apneic patients, aged between 9 and 14 years,diagnosed through type VI polysomnography (PSG). In partnership with thePsychology department at UNESP, participants will be assessed using the Brazilianvalidated versions of the SSRS (Social Skills Rating System, including the Social Skills,Problem Behaviors, and Academic Competence subscales) and the FDT (Five DigitTest). These assessments will be conducted before and after the orthodontic treatmentinvolving rapid maxillary expansion (Hyrax expander). Data normality will be assessedusing the Shapiro-Wilk test. Statistical analysis will evaluate test results at differenttime points using paired t-tests or Wilcoxon tests for comparisons. (AU)