In vitro and in vivo brain metabolites quantification using Magnetic Resonance Spectroscopy

• Grant number: 09/00270-2
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: June 01, 2009
• End date: May 31, 2012
• Field of knowledge: Engineering - Biomedical Engineering
• Principal Investigator: Carlos Ernesto Garrido Salmon
• Grantee: Felipe Rodrigues Barreto
• Host Institution: Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto (FFCLRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil

Abstract

Magnetic resonance spectroscopy is an important method used on brain metabolites quantification. In this project we propose in vitro quantification of main human metabolites found on 1H brain spectroscopy. Seeking for in vivo brain metabolic quantification, a spectrum database will be created to be used on different post-processing enviroment: MRUI, LC-Model, Achieva.

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

BARRETO, FELIPE R.; COSTA, THIAGO B. S.; LANDIM, RICARDO C. G.; CASTELLANO, GABRIELA; SALMON, CARLOS E. G.. P-31-MRS Using Visual Stimulation Protocols with Different Durations in Healthy Young Adult Subjects. Neurochemical Research, v. 39, n. 12, p. 2343-2350, DEC 2014. (09/00270-2, 09/10046-2, 11/01106-1, 05/56578-4)

FELIPE RODRIGUES BARRETO; MARIA CONCEPCIÓN GARCÍA OTADUY; CARLOS ERNESTO GARRIDO SALMON. Evaluation of nuclear magnetic resonance spectroscopy variability. Rev. Bras. Eng. Bioméd., v. 30, n. 3, p. 242-247, 2014-09-00. (09/00270-2, 05/56464-9)