Effects of two phospholipases A2, isolated from snake venom on NF-kappaB activation pathways related to COX-2 and mPGE synthase-1 expression: involvement of macrophage mannose receptors

• Grant number: 07/03337-5
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• Start date: April 01, 2008
• End date: March 31, 2011
• Field of knowledge: Biological Sciences - Pharmacology - General Pharmacology
• Principal Investigator: Catarina de Fatima Pereira Teixeira
• Grantee: Vanessa Moreira
• Host Institution: Instituto Butantan. Secretaria da Saúde (São Paulo - Estado). São Paulo , SP, Brazil

Scientific publications

(9)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

MOREIRA, VANESSA; LOMONTE, BRUNO; RAMIREZ VINOLO, MARCO AURELIO; CURI, RUI; MARIA GUTIERREZ, JOSE; TEIXEIRA, CATARINA. An Asp49 Phospholipase A(2) from Snake Venom Induces Cyclooxygenase-2 Expression and Prostaglandin E-2 Production via Activation of NF-kappa B, p38MAPK, and PKC in Macrophages. Mediators of Inflammation, 2014. (12/10653-9, 07/03337-5)

MOREIRA, VANESSA; TEIXEIRA, CATARINA; DA SILVA, HENRIQUE BORGES; D'IMPERIO LIMA, MARIA REGINA; DOS-SANTOS, MARIA CRISTINA. The crucial role of the MyD88 adaptor protein in the inflammatory response induced by Bothrops atrox venom. Toxicon, v. 67, p. 37-46, JUN 1 2013. (10/51150-4, 09/08559-1, 07/03337-5)

MOREIRA, VANESSA; GUTIERREZ, JOSE MARIA; AMARAL, RAFAELA BACCI; LOMONTE, BRUNO; PURGATTO, EDUARDO; TEIXEIRA, CATARINA. A phospholipase A(2) from Bothrops asper snake venom activates neutrophils in culture: Expression of cyclooxygenase-2 and PGE(2) biosynthesis. Toxicon, v. 57, n. 2, p. 288-296, FEB 2011. (07/03337-5)

MOREIRA, VANESSA; MAGGIO DE CASTRO SOUTO, POLLYANA CRISTINA; RAMIREZ VINOLO, MARCO AURELIO; LOMONTE, BRUNO; GUTIERREZ, JOSE MARIA; CURI, RUI; TEIXEIRA, CATARINA. A catalytically-inactive snake venom Lys49 phospholipase A(2) homolog induces expression of cyclooxygenase-2 and production of prostaglandins through selected signaling pathways in macrophages. European Journal of Pharmacology, v. 708, n. 1-3, p. 68-79, MAY 15 2013. (08/57898-0, 10/07630-1, 07/03337-5)

MOREIRA, VANESSA; GUTIERREZ, JOSE MARIA; LOMONTE, BRUNO; RAMIREZ VINOLO, MARCO AURELIO; CURI, RUI; LAMBEAU, GERARD; TEIXEIRA, CATARINA. 12-HETE is a regulator of PGE(2) production via COX-2 expression induced by a snake venom group IIA phospholipase A(2) in isolated peritoneal macrophages. Chemico-Biological Interactions, v. 317, FEB 1 2020. (12/10653-9, 07/03337-5)

GIANNOTTI, KARINA CRISTINA; LEIGUEZ, ELBIO; MOREIRA, VANESSA; NASCIMENTO, NEIDE GALVAO; LOMONTE, BRUNO; MARIA GUTIERREZ, JOSE; DE MELO, ROBSON LOPES; TEIXEIRA, CATARINA. A Lys49 Phospholipase A(2), Isolated from Bothrops asper Snake Venom, Induces Lipid Droplet Formation in Macrophages Which Depends on Distinct Signaling Pathways and the C-Terminal Region. BIOMED RESEARCH INTERNATIONAL, v. 2013, p. 14-pg., 2013-01-01. (07/03337-5, 10/06345-1, 11/21341-5)

GIANNOTTI, KARINA CRISTINA; LEIGUEZ, ELBIO; MOREIRA, VANESSA; NASCIMENTO, NEIDE GALVAO; LOMONTE, BRUNO; MARIA GUTIERREZ, JOSE; DE MELO, ROBSON LOPES; TEIXEIRA, CATARINA. A Lys49 Phospholipase A(2), Isolated from Bothrops asper Snake Venom, Induces Lipid Droplet Formation in Macrophages Which Depends on Distinct Signaling Pathways and the C-Terminal Region. BIOMED RESEARCH INTERNATIONAL, 2013. (11/21341-5, 07/03337-5, 10/06345-1)

MOREIRA, VANESSA; DOS-SANTOS, MARIA CRISTINA; NASCIMENTO, NEIDE GALVAO; DA SILVA, HENRIQUE BORGES; FERNANDES, CRISTINA MARIA; D'IMPERIO LIMA, MARIA REGINA; TEIXEIRA, CATARINA. Local inflammatory events induced by Bothrops atrox snake venom and the release of distinct classes of inflammatory mediators. Toxicon, v. 60, n. 1, p. 12-20, JUL 2012. (10/51150-4, 09/08559-1, 07/03337-5)

MOREIRA, VANESSA; LOMONTE, BRUNO; RAMIREZ VINOLO, MARCO AURELIO; CURI, RUI; MARIA GUTIERREZ, JOSE; TEIXEIRA, CATARINA. An Asp49 Phospholipase A(2) from Snake Venom Induces Cyclooxygenase-2 Expression and Prostaglandin E-2 Production via Activation of NF-kappa B, p38MAPK, and PKC in Macrophages. Mediators of Inflammation, v. 2014, p. 10-pg., 2014-01-01. (07/03337-5, 12/10653-9)