CARDIOVASCULAR EFFECTS DIFFERENTS DOSES IN MORFINE BY EPIDURAL INJECTED IN THE BITCHES FOR OVARIOSALPINGOHISTERCTOMY ACCOMPLISHMENT

• Grant number: 10/01961-6
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: May 01, 2010
• End date: April 30, 2011
• Field of knowledge: Agronomical Sciences - Veterinary Medicine - Animal Clinics and Surgery
• Principal Investigator: Valéria Nobre Leal de Souza Oliva
• Grantee: Mariana Werneck Fonseca
• Host Institution: Faculdade de Odontologia (FOA). Universidade Estadual Paulista (UNESP). Campus de Araçatuba. Araçatuba , SP, Brazil

Abstract

More positive aspects have been considered with the use of epidural lumbosacral to perform ovariosalpingohisterectomy in bitches, especially cardiorespiratory few changes, control postoperative pain, and diminished stress-operatively. Cardiography continuous monitoring during anesthesia is very important to monitor heart rate and rhythm. This study aims to investigate the cardiovascular changes of morphine at different doses of epidural bitches undergoing elective to OSH. Twenty-four female dogs will used, healthy and weighing between six and 25 kg-1 that will be allocated to three experimental groups, as follows: group 1 (n = 8), morphine (0.1 mg/kg-1), group 2 (n = 8): morphine (0.15 mg/kg-1) and group 3 (n = 8), morphine (0.2 mg/kg-1) in all groups the volumes will be supplemented with levobupivacaine to reach a total volume of 0.33 mL/kg-1 in all groups. Will have their heart function, blood pressure and blood lactate, and these parameters measured during the three experimental time. The results will be tabulated using SAS at a significance level 5% (p <0.05) and subjected to analysis of variance with repeated measures, nonparametric Kruskal - Wallis test, Friedman and Chi-square test.