Integrated in vitro and in silico strategies in the search for lead compounds agai...
Mutational analysis of active site residues in fumarate hydratase from Leishmania ...
Hot spots identification and molecular fragment screening as innovative approaches...
Development of leishmanicidal drugs based on the selective inhibition of the enzym...
Kinetic characterization and effect of mutations in the oligomeric interface of th...
Development of a model plataform for the search of leishmanicidal compounds based ...
Synthesis of a library of benzothiazolinic derivatives for the evaluation of inhib...