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ORAL MUCOSITIS IMPACT ON QUALITY OF LIFE AMONG PATIENTS SUBMITTED TO BONE MARROW TRANSPLANT

Grant number: 10/05225-2
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Start date: August 01, 2010
End date: July 31, 2012
Field of knowledge:Health Sciences - Dentistry - Social and Preventive Dentistry
Principal Investigator:Maria Gabriela Haye Biazevic
Grantee:Viviane Danelon Neves
Host Institution: Faculdade de Odontologia (FO). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

Oral mucositis constitutes a painful condition which frequently occurs in patients submitted to bone marrow transplant. It affects between 30 to 69% of the patients, having huge impact on their quality of life. The objective of the study is to verify the mucositis impact on oral health among patients submitted to bone marrow transplantat. Albert Einstein Hospital patients will be evaluated along 9 months in 4 different moments: a) 2 days before puncture; b) after 5 / 8 days, respectively, to autologous and allogeneic transplant; c) in days 12 / 20; and d) 30 days after patient discharge. Clinical evaluation will be performed using World Health Organization criteria; oral-health quality of life will be measured using OHIP-14; and PROMS scale will evaluate quality of life with regard oral mucositis symptoms. With the study, it is expected to discuss the quality of life improvement among patients that are being treated.

News published in Agência FAPESP Newsletter about the scholarship:
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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
BEZINELLI, L. M.; EDUARDO, F. P.; NEVES, V. D.; CORREA, L.; LOPES, R. M. G.; MICHEL-CROSATO, E.; HAMERSCHLAK, N.; BIAZEVIC, M. G. H.. Quality of life related to oral mucositis of patients undergoing haematopoietic stem cell transplantation and receiving specialised oral care with low-level laser therapy: a prospective observational study. EUROPEAN JOURNAL OF CANCER CARE, v. 25, n. 4, p. 668-674, . (10/05225-2)