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Effects of employment of resistant starch from extrusion process on glycemic control of diabetic dogs

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Author(s):
Fábio Alves Teixeira
Total Authors: 1
Document type: Master's Dissertation
Press: São Paulo.
Institution: Universidade de São Paulo (USP). Faculdade de Medicina Veterinária e Zootecnia (FMVZ/SBD)
Defense date:
Examining board members:
Marcio Antonio Brunetto; Áulus Cavaliéri Carciofi; Ricardo Duarte Silva
Advisor: Marcio Antonio Brunetto
Abstract

Diabetes mellitus (DM) is a disease that causes hyperglycemia by insulin deficiency, which can lead to death. Administration of insulin and feeding management that minimizes glycemic fluctuation are the mainstay of treatment. The amount, source and starch processing may interfere on postprandial glycaemia in dogs, but few researches have evaluated these aspects in diabetic dogs. This study aimed to evaluate the effects of less processed starch, during extrusion process, on glycemic control of diabetic dogs. It was included 15 diabetic dogs without other disorders, selected in routine from Veterinary Hospital (School of Veterinary Medicine and Animal Science University of São Paulo). The animals were fed three extruded dry feed: Ba (high fiber and protein, low fat and moderate starch from various sources), Co (pea and barley as starch sources, moderate fat, starch, protein and fiber) and LP (use corn as a source of starch and was less processed to generate lower gelatinization index of starch). Glucose curve was performed by a continuous glucose measurement system for 48 hours, after 60 days of treatment in every diet and under the same dose of insulin. Statistical tests parametrics and non-parametrics were used to compare the amount of food and nutrient intake and dietary effects on variables of glucose and lipids concentration. The animals fed with Co presented less starch intake (p<0.01) compared to LP, and between Co and LP, Co resulted in greater time under hypoglycaemia (p<0.01), lesser time under hyperglycemia (p<0.01) and remained similar values of cholesterolemia compared to Ba and greater than LP (p=0.01). Thus, it was concluded that the diet with slow digestion starch (pea and barley) resulted in better glycemic and lipidic parameters in diabetic dogs when compared to based corn diet processed to have lower starch gelatinization index. (AU)

FAPESP's process: 14/02749-1 - Effects on employment of resistant starch derived from extrusion process on glycemic control in diabetic dogs
Grantee:Fabio Alves Teixeira
Support Opportunities: Scholarships in Brazil - Master