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| Author(s): |
Dennis Galasso Diego
Total Authors: 1
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| Document type: | Doctoral Thesis |
| Press: | São Paulo. |
| Institution: | Universidade de São Paulo (USP). Conjunto das Químicas (IQ e FCF) (CQ/DBDCQ) |
| Defense date: | 2006-04-03 |
| Examining board members: |
Joao Valdir Comasseto;
Ivan Persio de Arruda Campos;
Luiz Henrique Catalani;
Vicente de Paulo Emerenciano;
Paulo Henrique Menezes da Silva
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| Advisor: | Joao Valdir Comasseto |
| Abstract | |
The main goal of the first part of this project is the total synthesis of isocicutoxin (scheme 1) and some insects\' sexual pheromones by means of some reactions already studied by our group (scheme 2). (See PDF) The key steps for the synthesis of isocicutoxin were a coupling reaction between a diyne and a vinylic telluride, followed by a Wittig reaction. The key steps for the synthesis ofthe sexual pheromones were a cross coupling reaction between a vinylic telluride and an organocuprate, followed by a SN2 reaction with a Grignard reagent. The mam goal of the second part of the project lS the bibliographic reVleW and the systematization of 1H, 13C and 125Te data of tellurium compounds. The ligands containing tellurium had their NMR and their effective shielding values analyzed (Scheme 3). Using specialized software, a database was developed, which allowed the prediction of NMR 13C and 125Te spectra. (AU) | |