Full text
| |
| Author(s): |
Leonardo Alves Pasqua
Total Authors: 1
|
| Document type: | Master's Dissertation |
| Press: | São Paulo. |
| Institution: | Universidade de São Paulo (USP). Escola de Educação Física e Esportes (EEFE/BT) |
| Defense date: | 2013-04-10 |
| Examining board members: |
Rômulo Cássio de Moraes Bertuzzi;
Gustavo Gomes de Araujo;
Adriano Eduardo Lima da Silva
|
| Advisor: | Rômulo Cássio de Moraes Bertuzzi |
| Abstract | |
The aim of the present study was to investigate the relationship among the genotypes of the ACTN3 gene and physiological and neuromuscular parameters related to aerobic fitness and endurance performance. One hundred and fifty male physically active subjects performed the following tests: a) a maximal incremental test to determine maximal oxygen consumption, peak velocity, ventilatory threshold and respiratory compensation point; b) two constant speed tests at 10 km.h-1 and 12 km.h-1 to determine running economy; c) one repetition maximum in the leg press to determine the maximal dynamic strength of the lower limbs; d) vertical jump test to determine the maximum power of the lower limbs and; e) genotyping for the ACTN3 gene polymorphism. Our main results were a higher frequency of the XX genotypes among the individuals with the highest speeds associated to ventilatory threshold and to the respiratory compensation point. It was observed a higher frequency of at least one copy of the X allele (RX and XX genotypes) among the more economical individuals. These results suggest that the XX genotype of the ACTN3 gene seems to be associated with physiological variables related with the aerobic fitness, mainly those determined in submaximal intensities (AU) | |
| FAPESP's process: | 10/13913-6 - Running economy and muscle strength: a relationship with ACTN3 gene R577X polymorphism |
| Grantee: | Leonardo Alves Pasqua |
| Support Opportunities: | Scholarships in Brazil - Master |