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| Author(s): |
Andréia Coutinho Facin
Total Authors: 1
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| Document type: | Master's Dissertation |
| Press: | Jaboticabal. 2020-09-04. |
| Institution: | Universidade Estadual Paulista (Unesp). Faculdade de Ciências Agrárias e Veterinárias. Jaboticabal |
| Defense date: | 2020-07-30 |
| Advisor: | Paola Castro Moraes |
| Abstract | |
The present study aimed to evaluate the hepatic and spleen stiffness of brachycephalic dogs and its correlation with the brachycephalic syndrome. The tissue elasticity was evaluated by ARFI (Acoustic radiation force impulse) elastography, with convex and linear multifrequential transducers and specific software. Forty-eight brachycephalic and 22 mesocephalic dogs, with an age range between one to six years old and weight range also pre-define. The brachycephalic breeds showed values of liver stiffness (medial lobes: 1.52 m/s ± 0.36; left lateral lobe: 1.47 m/s ± 0.47; right lateral lobe: 1.20 m/s ± 0.29 and caudate lobe: 1.23 m/s ± 0.39) and spleen stiffness (2.51 m/s ± 0.45) significantly higher than the mesocephalic dogs (Liver: medial lobes: 0.96 m/s ± 0.10, left lateral lobe: 0.93 m/s ± 0.11, right lateral lobe: 0.74 m/s ± 0.08, caudate lobe: 0.76 m/s ± 0.10; spleen: 2.29 m/s ± 0.34) by the analyses of variances ANOVA. A principal component analysis was performed in which two components (shear wave velocities of the left lateral, medial and caudate lobes versus hemoglobin, hematocrit erythrocytes and ALT) explained 70% of the variances between the groups. Brachycephalic dogs had higher spleen and liver stiffness when compared with mesocephalic dogs. (AU) | |
| FAPESP's process: | 17/24809-4 - ARFI elastography of the hepatic and splenic tissues of canine patients affected by brachycephalic syndrome |
| Grantee: | Andréia Coutinho Facin |
| Support Opportunities: | Scholarships in Brazil - Master |