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| Author(s): |
Amanda Heloisa Santana da Silva
Total Authors: 1
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| Document type: | Master's Dissertation |
| Press: | Ribeirão Preto. |
| Institution: | Universidade de São Paulo (USP). Escola de Enfermagem de Ribeirão Preto (PCARP/BC) |
| Defense date: | 2019-07-10 |
| Examining board members: |
Ana Carolina Guidorizzi Zanetti;
Marcos Hortes Nisihara Chagas;
Bianca Cristina Ciccone Giacon;
Kelly Graziani Giacchero Vedana
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| Advisor: | Ana Carolina Guidorizzi Zanetti; Rosana Shuhama |
| Abstract | |
Relapses and rehospitalizations may worsen the patient\'s prognosis in the first episode of psychosis (FEP) and affect his/her quality of life and the quality of life of patients\' family members. Thus, this study aimed to evaluate the related factors to psychotic relapses in FEP patients, such as the family environment: levels of expressed emotion (EE) and its components - critical comments (CC) and emotional overinvolvement (EOI); adherence to drug treatment; use of psychoactive substances (PAS); and the presence of depression. A prospective cohort study with 65 FEP outpatients followed-up at a university hospital in the state of São Paulo, Brazil and their relatives. Data were collected through face-to-face interviews with the patients and their relatives from July 2017 to December 2018. At baseline were applied to the family members a sociodemographic data questionnaire and the Brazilian version of Family Questionnaire (FQ-VPB). For the FEP patients were applied a sociodemographic and clinical data questionnaire, the Morisky Medication Adherence Scale (MMAS); the Brazilian version of Alcohol, Smoking and Substance Involvement Screening Test (ASSIST/WHO); the Severity of Dependence Scale (SDS) to evaluate the cannabis use and the Module A of Mini International Neuropsychiatric Interview to evaluate the presence of depression. Additionally, patients were submitted to evaluations regarding the presence of relapses through the Brief Psychiatric Rating Scale (BPRS) during six-months after the initial interview (T0 to T6). Descriptive statistics, bivariate analysis and binary logistic regression were used to analyze the data. The level of significance was ? = 0.05. Regarding the results, 29.2% of the patients in the FEP presented relapse of psychotic symptoms during the sixmonth follow-up period. Binary logistic regression analysis suggests that family environment with high levels of EOI, the presence of depressive symptoms and cannabis use in the last three months by patients with early psychosis were predictors of relapse occurrence during six-months of follow-up. The results of this study may help in the implementation of actions aimed to relapse prevention and health promotion for patients in FEP and their families (AU) | |
| FAPESP's process: | 17/13462-3 - Relapses of patients with first-episode psychosis and related factors |
| Grantee: | Amanda Heloisa Santana da Silva |
| Support Opportunities: | Scholarships in Brazil - Master |