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| Author(s): |
Carlos Dellavechia de Carvalho
Total Authors: 1
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| Document type: | Doctoral Thesis |
| Press: | Ribeirão Preto. |
| Institution: | Universidade de São Paulo (USP). Faculdade de Medicina de Ribeirão Preto (PCARP/BC) |
| Defense date: | 2025-08-05 |
| Examining board members: |
Marcelo Papoti;
Carlos Fernando Pereira da Silva Herrero;
Pedro Paulo Menezes Scariot
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| Advisor: | Marcelo Papoti |
| Abstract | |
This thesis aims to present the physiological, biomolecular, and performance effects of the inter-effort recovery hypoxia (IEH) model in humans and an animal model. The experiments aimed to present i) through a systematic review of the literature, the acute effects of different training models in intermittent hypoxia; ii) acute physiological effects of IEH in a high-intensity interval training (HIIT) session on running in young adult humans iii) acute physiological effects of EHI in a HIIT session on tethered running in a deep-water pool in young adult humans iv) effects of the combination of IEH with blood flow restriction in an acute repeated sprint session in young adult humans v) acute physiological and molecular effects of IEH in a HIIT session in Wistar rats vi) chronic physiological adaptations of IEH associated with moderate-intensity training in patients convalescent with COVID-19 vii) chronic physiological and molecular adaptations of IEH associated with a HIIT program in Wistar rats. Among the main results, it is worth highlighting that, in acute physical exercise sessions, the EHI model, despite changes in physiological parameters, did not result in impaired performance in any of the contexts studied. Chronically, despite the positive evidence, it is still unclear whether this strategy is effective in improving physical performance, compared to normoxic training. (AU) | |
| FAPESP's process: | 20/11573-5 - Effects of combined training with intermittent hypoxia on physiological, molecular responses and performance of Wistar rats |
| Grantee: | Carlos Dellavechia de Carvalho |
| Support Opportunities: | Scholarships in Brazil - Doctorate |