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Prospective study of the treatment of chronically infected hip replacements with and without the use of an antibiotic-loaded acrylic cement spacer

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Author(s):
Henrique Antonio Berwanger de Amorim Cabrita
Total Authors: 1
Document type: Doctoral Thesis
Press: São Paulo. , gráficos, ilustrações, tabelas.
Institution: Universidade de São Paulo (USP). Faculdade de Medicina (FM/SBD)
Defense date:
Examining board members:
Olavo Pires de Camargo; Rudelli Sergio Andrea Aristide; Alberto Tesconi Croci; Sérgio Nogueira Drumond; Ana Lucia Lei Munhoz Lima
Advisor: Olavo Pires de Camargo
Field of knowledge: Health Sciences - Medicine
Indexed in: Banco de Dados Bibliográficos da USP-DEDALUS; Biblioteca Digital de Teses e Dissertações - USP
Location: Universidade de São Paulo. Biblioteca Central da Faculdade de Medicina ; FM/W4.DB8 SP.USP FM-2; C123est
Abstract

We report a prospective study of 61 patients with chronically deep infected hip replacements with actively discharging sinuses, treated with a two-stage revision protocol, with and without a cement spacer impregnated with vancomycin. The average follow-up was two years and eleven months. Twenty-five patients were treated without a spacer and seven had recurrence of infection. Thirty-three patients were treated with a spacer and three had recurrence of infection. The average Harris Hip score increased from 19,3 to 69,0 on the non-spacer patients and from 19,7 to 75,2 on the spacer group. At the end of the study, the success rate was 86,1% for the spacer group and 33,3% for the non-spacer group. The use of the spacer increased the results of the two-stage chronic infected hip replacements (AU)