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| Author(s): |
Simone Cristina Motta
Total Authors: 1
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| Document type: | Doctoral Thesis |
| Press: | São Paulo. |
| Institution: | Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB/SDI) |
| Defense date: | 2010-07-30 |
| Examining board members: |
Newton Sabino Canteras;
Antonio de Pádua Carobrez;
Sara Joyce Shammah Lagnado;
Sandra Regina Mota Ortiz;
Claudio Antonio Barbosa de Toledo
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| Advisor: | Newton Sabino Canteras |
| Abstract | |
In nature, animals express fear responses toward a predator or a co-specific and not much is known about the neural organization of intra-specific defense. Therefore, the aim of this work was to analyze the role that the hypothalamus plays during the intra-specific defense expression. We observed that the dorsal premammilary nucleus is also mobilized during the agonistic encounter, but a different portion. Dorsal premammilary nucleus lesioned intruders led to important defense alterations, almost abolishing passive forms of defensive behavior. Notably, regions in lateral hypothalamus are particularly important for activating the dorsal premammilary nucleus and its efferent projection to the dorsomedial column of periaqueductal gray matter is the most important outcome for the defensive behavior expression. Concluding, the hypothalamus is fundamental for the neural organization of intra-specific defense and inter and intra-specific defensive behaviors are organized by distinct neural pathways. (AU) | |
| FAPESP's process: | 05/54511-0 - Analysis of hypothalamic systems involved in the organization of offensive aggression |
| Grantee: | Simone Cristina Motta |
| Support Opportunities: | Scholarships in Brazil - Doctorate |