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| Author(s): |
Victor Rafael Castillo Merino
Total Authors: 1
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| Document type: | Doctoral Thesis |
| Press: | São Paulo. |
| Institution: | Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB/SDI) |
| Defense date: | 2012-09-27 |
| Examining board members: |
Mario Julio Avila Campos;
Tania Aparecida Tardelli Gomes do Amaral;
Rita de Cassia Cafe Ferreira;
Alfredo Elias Gilio;
Roxane Maria Fontes Piazza
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| Advisor: | Mario Julio Avila Campos; Viviane Nakano |
| Abstract | |
Diarrhea is a major cause of mortality and morbidity worldwide achieving children < 5 years old, and is second cause of death in emerging countries. Intestinal anaerobes like enterotoxigenic B. fragilis and Clostridium difficile are associated to acute diarrhea, as well as diarreiogenic Escherichia coli, Salmonella spp., Shigella spp. and Yersinia enterocolitica. In this study, it was evaluated quantitatively the presence of enteropathogens directly from fezes. Stools specimens from children with (110) and without (150) diarrhea were collected. All enteropathogens were detected in children with and without diarrhea except Salmonella spp. and Y. enterocolitica that were only observed in diarrheal fezes. This results suggest a tight bacterial relationship in both groups evaluated. The presence of EPEH/EHEC and Shigella spp./EIEC show statistically significant values. (AU) | |
| FAPESP's process: | 07/03655-7 - Quantitative evaluation of Bacteroides fragilis enterotoxigenic strains and respective BFT gene subtypes in immunocompetent children with and without acute diarrhea |
| Grantee: | Victor Rafael Castillo Merino |
| Support Opportunities: | Scholarships in Brazil - Doctorate (Direct) |