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| Author(s): |
Talita da Silva Mendes de Farias
Total Authors: 1
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| Document type: | Master's Dissertation |
| Press: | São Paulo. |
| Institution: | Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB/SDI) |
| Defense date: | 2010-11-24 |
| Examining board members: |
Fabio Bessa Lima;
Fernanda Gaspar do Amaral;
Melissa Moreira Zanquetta
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| Advisor: | Fabio Bessa Lima |
| Abstract | |
The objective was to investigate whether there rhythmicity of events in lipolytic and lipogenic TA peri-epididymal and characterize whether pinealectomy interferes with this process. The sacrifice of animals, controls and pinealectomized was performed every four hours. In relation to lipogenesis observed significant differences between the times tested, however, the comparison between groups showed no significant differences, indicating that pinealectomy does not intervene in the metabolic process of WAT. The study of lipolysis showed that there are some significant differences between the times, however, pinealectomy did not affect the rhythms of this process. The use of COSINOR program for analysis of the existence of rhythms, suggest that there is a rhythm in both lipogenesis and lipolysis, but that does not occur in a circadian manner, i.e., does not occur at intervals of 24 ± 4. We also found no significant differences between groups when analyzed food intake, water intake and body weight evolution. (AU) | |